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Postdoc in Computational Biology: Leading the EpiFlaMe Consortium

University of Salzburg↗
📍 Salzburg▣ Full-time · On-site (40 hours/week)◷ Postdoctoral▦ Posted: 2026-10-30Closes in 27 days

Job Description

The group: The candidate will be part of the Computational Systems Biology group at the University of Salzburg, headed by Nikolaus Fortelny (https://plus.ac.at/fortelny). The group is focused on integrating single-cell/spatial multi-omics data with biological knowledge using AI/ML and other computational approaches in cancer and immunology research. The group focuses on approaches that produce robust, reliable, and ideally interpretable results.

The project: EpiFlaMe (Memory in Epithelial Cells - Organ Specificity and Cancer: https://plus.ac.at/epiflame) is a large consortium of seven research groups dedicated to understanding inflammatory memory in epithelia. The postdoc will be supported by a bioinformatics technician to coordinate and perform integrative bioinformatic data analysis of multi-omics profiles generated by these various groups, focusing on producing a consortium flag-ship publication (similar to Fortelny et al., Nature Immunology, 2024). The project focuses on understanding epithelial inflammatory memory and its relationship with cancer development. Using multi-omics profiling, innovative organoid cell cultures and in-vivo models, the consortium will create the first systematic molecular map of inflammatory memory in epithelial cells across multiple organs. The goal of the EpiFlaMe research program is to lay the foundation for future therapies that can treat chronic inflammatory diseases and help prevent tumor formation in an organ-specific way.

The place: The city of Salzburg has ample natural and cultural attractions as well as fast connections to Vienna and Munich. It is surrounded by lakes and mountains, with various opportunities for recreational and sports activities. The university has 18,000 students and a highly collaborative research environment in both biomedical and computational sciences.

Key Responsibilities

  • Coordinate integrative bioinformatic data analysis of multi-omics profiles generated by the seven EpiFlaMe consortium groups • Lead the analysis towards a consortium flagship publication • Work with a supporting bioinformatics technician • Participate in conferences and project meetings

Qualifications

  • PhD in biology, bioinformatics, biotechnology, computer science, statistics, physics, or similar

Experience

Experience with (multi-)omics integrative data analysis, single-cell / spatial data, and/or CRISPR screens

Skills Required

  • Programming in R/Python • Quantitative skills: statistics, AI/ML, network biology • Understanding of and interest in immunology • Excellent scientific thinking and communication, high motivation and drive • Excellent English and communication skills, especially with wet-lab biologists

Additional Information

CompanyUniversity of Salzburg
LocationSalzburg
Job TypeFull-time · On-site (40 hours/week)
Experience LevelPostdoctoral
Salary / StipendAccording to Austrian funding regulations
Application Deadline2026-11-27
Posted Date2026-10-30
Company Websitehttps://www.plus.ac.at ↗
SourceOfficial Career Page ↗
Start DateAs soon as possible Duration: Until end of 2029 (project may then be prolonged for 4 years) Working Hours: 40 hours/week Salary: According to Austrian funding regulations Place of Work: Salzburg, Austria Research Group: Computational Systems Biology (Prof. Nikolaus Fortelny) Hiring: Rolling basis Benefits: Austrian social benefits (holidays, health insurance), training courses, conferences

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